IgG levels in mother-father-cord trios. Evidence for a large reduction of maternal IgG at birth.
نویسندگان
چکیده
Cord plasmas have a higher concentration of IgG than do the mothers, although autologous, fetal immunoglobulin G is only a small fraction of the neonate's complement. Maternal IgG levels are significantly lower than the nonpregnant adult female, a loss of about one third, which cannot be explained completely by maternal immunization of the fetus.
منابع مشابه
Gn allotypes in mother-father-cord trios. A selective transfer of autologous, fetal IgG to the mother.
When tested at a standard dilution (1:30), mother-cord Gm phenotypes are identical. A more sensitive assay reveals that the fetus does possess paternal antigen, that is, does produce small amounts of autologous IgG. The paternal antigens, in both the mother and the cord plasma, appear in a mosaic, one that suggests the fetus has the ability to selectively transfer his own IgG subclasses to the ...
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عنوان ژورنال:
- Vox sanguinis
دوره 37 2 شماره
صفحات -
تاریخ انتشار 1979